Theoretical Studies of Proton-transfer Tautomerism of 2-hydroxylpyridine;
2-羟基吡啶质子转移异构化的理论研究
Using 2,6-dichloropyridine as material,through a nucleophilic reaction and an electrophilic reaction,3,5,6-trichloro-2-pyridinol with a high yield of 89% was synthesized by using FeCl_3/I_2 as catalyzer.
以2,6-二氯吡啶为原料,经亲核和亲电两步反应,采用FeC l3/I2催化的新工艺合成了3,5,6-三氯-2-羟基吡啶,获得了89%的高产率。