The nonsense mutation is a specific type of gene mutation.
无义突变(nonsense mutation)是一类特定类型的基因突变。
Method1 Targeted correction of nonsense mutation in LDLR in HepG2 cell1.
方法1 HepG2细胞LDLR基因无义突变模型原位修复1。
Conclusions:Two novel missense mutaions and one nonsense mutation in the LQTS genes are identified in 5 LQTS families.
其中HERG基因无义突变Y616X引起mRNA表达量减少,可能受无义突变介导的RNA降解(Nonsense Mediated Decay,NMD)机制有关,从而引起较轻微的临床症状。
The experiment of adaptive mutation was performed by using Escherichia coli GM133 rif as test cells and HB214 strr as scavenger cells.
本研究采用大肠杆菌GM133 rif~r细胞和营养收集细胞HB214 sir~r进行适应性突变实验。
The research based on the Escherichia coli FC40 showed that adaptive mutations required the enzymes of RecBCD recombination pathway and some unknown proteins of SOS response,and the mutation spectrum of lac + revertants is single-base deletions in the small mononucleotide repeats.
基于大肠杆菌FC40菌株的研究结果表明 ,适应性突变依赖RecBCD重组途径的酶 ,要求SOS反应的部分基因功能 ,lac+ 回复突变序列都是在单核苷酸短重复序列处的一个碱基缺失。
neutral mutation
中和突变[无适应意义的突变]
The Clinical Prevelence of FLT3 Mutations in Acute Leukemia;
FLT3突变在急性白血病中的临床意义
Significances of Caveolin-1 Gene Expression and Mutation in Gastric Carcinomas;
胃癌中Caveolin-1基因表达及突变的意义
Significace of PIK3CA Gene Mutention in Cervical Carcinoma
PIK3CA在宫颈癌组织中的突变及意义
The Expression of PAX2 and Mutant P53 in Endometrial Carcinoma and Its Clinical Significance;
PAX2和突变型P53在子宫内膜癌中的表达和临床意义
Expression and Clinical Significance of P27～(kip1) and Mutated p53 in Testicular Seminoma;
P27～（kip1）和突变型p53在睾丸精原细胞瘤中表达及其临床意义的研究
Clinicopathological Significance of Maspin and Mutant p53 Protein Expression in Gastric Cancer;
胃癌中maspin和突变型p53蛋白的表达及临床病理学意义
The Significance of ABCB11 and ATP8B1 Mutations in Infants with Progressive Intrahepatic Cholestasis and Low GGT
ABCB11和ATP8B1基因突变在低GGT进行性肝内胆汁淤积症中的意义
Detection and Its Clinical Significance of EGFR Gene Mutation and Gene Amplification in 187 Patients with Non-small Cell Lung Cancer
187例非小细胞肺癌中EGFR基因突变和扩增的检测及其临床意义
On the Breaking Meaning and Gradual Meaning in the Adj+up Structure;
论“Adj+起来”结构中的突变义与渐变义
Changes of collagenase in herniation of lumbar intervertebral disc and its significance
胶原酶在腰间盘突出症中的变化及意义
Expression and Clinical Significance of CD40 Mutant in Gastric Cancer;
CD40分子突变体在胃癌中的表达及临床意义
Expression of mtP53 and HSP70 in Epithelial Ovarian Carcinoma and Clinical Value;
HSP70、突变型P53在卵巢癌中的表达及临床意义
Mutation and Protein Expression in PTEN Gene in Endometrial Carcinoma and Their Significance;
子宫内膜癌中PTEN基因的突变、表达及其临床意义
The Significance of SLC25A13 Gene Mutation in Chinese Infants with Intrahepatic Cholestasis;
SLC25A13基因突变在婴儿肝内胆汁淤积症中的意义
Detection of the mutation of Caveolin-1 gene in gastric cancer tissues
胃癌组织中Caveolin-1基因突变的检测及意义
The sudden jumps and hysteresis are phenomenologically analyzed by the catastrophe theory.
并用突变理论唯象地解释了其中出现的突变和滞后效应。
VARIATIONS IN THE EOLIAN ENVIRONMENT OF NORTH AMERICA DURING THE LAST GLACIAL MAXIMUM AND THEIR SIGNIFICANCE IN THE GLOBAL ABRUPT CLIMATIC EVENTS
末次盛冰期北美风成环境变化及其在全球气候突变事件中的意义