Expression and its clinical significance of receptor tyrosine kinase EphB1 in gastric carcinoma
受体酪氨酸激酶EphB1在胃癌中的表达及其临床意义
Mer is one member of Axl receptor tyrosine kinase family, and its ligand Gas6 can stimulate activity of Mer receptor tyrosine kinase after binding it, and then activate the downstream signal transduction pathway, Mer participates in cell inflammation, apoptosis, tumorigenesis, thrombosis and hemostasis.
Mer是Axl受体酪氨酸激酶家族中的一员,其受体Gas6和Mer结合后可以激活Mer的酪氨酸激酶活性,并激活下游信号传导途径,在细胞炎症、凋亡、血液肿瘤发生发展以及血栓于止血等方面发挥作用。
FLT3,a member of receptor tyrosine kinase III family,is primarily expressed by hematopoietic cells and plays a significant role in hematopoiesis and leukemogenesis.
FMS-like Tyrosine Kinase 3(FLT3)是一种受体酪氨酸激酶,在造血干细胞、前体B细胞等的增殖、分化以及存活中具有重要作用。
Receptor tyrosine kinase (RTK) inhibitors targeting VEGF receptor is one of the most promising agents.
血管内皮细胞生长因子 (VEGF)是体内活性最强、专属性最高的促血管生成因子 ,故成为寻找血管生成抑制剂的重要靶点 ,其中靶向 VEGF受体酪氨酸激酶的抑制剂令人最为关注。
Our study is aimed to investigate whether EphA3,which is a member of RTK family,can play a role in PCa progression and whether it can promote the transition of PCa from androgen dependent stage to androgen independent stage as well as the mechanism of its function.
本课题旨在阐明受体酪氨酸激酶家族分子EphA3能否在前列腺癌进展中发挥作用,能否促进前列腺癌从雄激素依赖向雄激素非依赖的转变,并探索其发挥作用的分子机制,为发现新的前列腺癌相关信号转导途径,发现新的药物靶标和诊断治疗方法奠定基础。
Modulation of potassium channels by receptor tyrosine kinases:recent progress;
受体酪氨酸激酶调节钾离子通道功能的研究进展
The epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases have close connection with the initiation, progression and progn osis of various malignancies.
表皮生长因子受体 (EGFR)家族的受体酪氨酸激酶与多种恶性肿瘤的发生、发展及预后等密切相关。
Objective To explore the effects of the neonatal handling and the enriched environment on nerve growth factor(NGF)and its tyrosine kinase receptor A(Trk A)in the forehead cortex and hippocampus of neonatal rats.
目的探讨早期触摸和环境刺激对新生鼠额皮质、海马神经生长因子(nerve growth factor,NGF)及酪氨酸激酶受体A(tyrosine kinase receptor A,Trk A)的影响。
With the aim to examine the distribution of high-affinity neurotrophin receptors (tyrosine kinase receptors, TrkA, TrkB and TrkC) in the rat Scapa’s ganglion (vestibular ganglion, VG), Avidin-Biotin-peroxidase Complex (ABC) method of immunohistochemistry with diaminobenzidine (DAB) as the chromogen to identify the immunoreactivities was employed in the present study.
采用免疫组织化学的卵白素-生物素-HRP复合物(ABC)法,以二氨基联苯胺(DAB)为呈色剂,观察高亲和性的神经营养物质受体(酪氨酸激酶受体),即TrkA, TrkB和TrkC在大鼠Scapa神经节(前庭神经节,VG)中的分布。
The progresses on the study of neurotrophic factors such as neurotrophins and their functional receptors tyrosine kinase receptors (Trks TrkA, TrkB, TrkC) have been made rapidly.
近年来， 对神经营养因子（ｎｅｕｒｏｔｒｏｐｈｉｃｆａｃｔｏｒｓ） 尤其是神经营养素（ｎｅｕｒｏｔｒｏｐｈｉｎｓ， Ｎ Ｔｓ） 及其功能性受体———酪氨酸激酶受体 Ｔｒｋ Ａ、 Ｔｒｋ Ｂ、 Ｔｒｋ Ｃ 的研究进展迅速。
Expression of receptor tyrosine kinase EphA1 in gastric cancer and its clinicopathological significance
受体酪氨酸激酶EphA1 mRNA在胃癌中的表达
c-Abl Stabilizes Estrogen Receptor by Phosphorylation and Regulates Its Transcription Activity;
c-Abl非受体酪氨酸激酶调节ERα转录活性的研究
Molecular targeted therapies:targeting receptor tyrosine kinases in the treatment of gastric cancer
靶向于受体酪氨酸激酶的胃癌分子靶向治疗
Advances in the inhibitors of FLT-3 receptor tyrosine kinase
FLT-3受体酪氨酸激酶抑制剂的研究进展
Expression of receptor tyrosine kinase EphA7 in gastric carcinoma and its clinical significances
受体酪氨酸激酶EphA7基因在胃癌中的表达及意义
Effect of Receptor Protein-tyrosine Kinases in Tumor Angiogenesis
受体酪氨酸激酶在肿瘤血管新生中的作用
Progress in research of multi-targeted inhibitors of receptor tyrosine kinase
多靶点受体酪氨酸激酶抑制剂的研究进展
Preparation of Monoclonal Antibodies Against RON Receptor Tyrosine Kinase;
抗RON受体酪氨酸激酶单克隆抗体的制备和生物学特性研究
The inhibitor of VEGF receptor tyrosine kinase was introduced in detail.
详细介绍了VEGF受体酪氨酸激酶抑制剂的研究进展。
The Effect of Receptor Tyrosine Kinase Inhibitor on Repair Tissue in Chondrocyte and Osteoarthritis Cartilage;
受体酪氨酸激酶抑制剂在软骨修复中的作用研究
Prevalence and Clinical Significance of Type Ⅲ Receptor Tyrosine Kinases in Acute Leukemia;
Ⅲ型受体酪氨酸激酶与急性白血病的关系及临床意义
The Study on the Transcripition Activity Modulation of C/EBPβ by c-Abl Non-Receptor Tyrosine Kinase;
c-Abl非受体酪氨酸激酶调节C/EBPβ转录活性的研究
The Experimental Study on the Effect of Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor on Polycystic Kidney Disease;
表皮生长因子受体酪氨酸激酶抑制剂治疗多囊肾病的实验研究
The Significance of Expression Angs/Tie-2 System in Leukemia;
白血病患者中血管生成素/受体酪氨酸激酶的表达及其意义
Study of 4-AnilinoquinazoIines as Inhibitors of Tyrosine Kinase of the Epidermal Growth Factor Receptor;
4-苯胺基喹唑啉类表皮生长因子受体酪氨酸激酶抑制剂的研究
Functional Interaction between HAX-1 and c-Abl Non-receptor Tyrosine Kinase;
HAX-1与c-Abl非受体酪氨酸激酶相互作用及其生物学意义
The Roles of Tyro 3 Subfamily of Receptor Tyrosine Kinases in Regulating Hematopoiesis;
Tyro 3亚家族受体酪氨酸激酶在调节造血中的功能
Functional Interaction between c-Abl Non-receptor Tyrosine Kinase and FHL2
c-Abl非受体酪氨酸激酶与FHL2相互作用及其生物学意义