Objective To synthesize raloxifene hydrochloride,which is a selective estrogen receptor modulator.
目的合成选择性雌激素受体调节剂盐酸雷洛昔芬。
In spite of many studiesabout 5-hydroxytryptamine receptor moderator in recent ten years, the exacteffeciveness and safety has no distinct conclusion.
近十多年来，5-羟色胺受体调节剂的研究较多，但对IBS的确切疗效和安全性尚无明确的定论。
In recent years,advanced research on selective estrogen receptor modulators has been made,making the treatment of menopausal syndrome safer and more effective.
近年来,选择性雌激素受体调节剂的研究取得一定进展,将使更年期综合征的治疗更趋安全有效。
Selective estrogen receptor modulators(SERMs) are structurally different compounds that interact with intracellular estrogen receptors in target organs as estrogen receptor agonists and antagonists.
选择性雌激素受体调节剂(SERMs)是一类结构不同的化合物,能与靶器官细胞内的雌激素受体结合而发挥雌激素受体激动剂和拮抗剂的作用。
Advances on mechanisms of selective estrogen receptor modulators and their therapy of postmenopausal osteoporosis;
选择性雌激素受体调节剂的作用机制及其治疗绝经后骨质疏松症的研究现状
AIM: To discuss the influence of selective estrogen receptor modulator(SERM) raloxifene(RAL) on the expression of TNF-α in cancellous bone and bone mineral density (BMD) loss in ovariectomized rats.
目的选择性雌激素受体调节剂(SERM)—雷诺昔酚(RAL)对去卵巢大鼠骨密度及松质骨中TNF-α表达的影响。
Objective To discuss the influence of selective estrogen receptor modulator(SERM) on Expression of TNF-α in cancellated bone and bone mineral density and the parameters of bone morphometry in ovariectomized rats.
目的了解选择性雌激素受体调节剂(SERM)对去卵巢大鼠骨组织形态计量学指标、骨密度及松质骨中TNF-α表达的影响。