Development of an assay for screening β amyloid aggregation inhibitors in vitro and study on inhibitive activity of friedelin;
β淀粉样肽聚集抑制剂体外筛选模型的建立及木栓酮抑制活性研究
A new furostanol glycoside and other two known compounds were isolated from the 70% EtOH extract of the rhizomes of Smilax scobinicaulis,which were identified as 26OβDglucopyranosyl(25R)furost5ene3β,17αdiol3OαLrhamnopyranoside,friedelin and stigmasterol by chemical and spectral methods such as IR,MS,1HNMR,13CNMR,HMQC and HMBC.
从百合科天然药用植物黑刺菝葜根茎的体积分数70%醇提取物中分离得到1个新呋甾烷甙和2个已知化合物,经光谱技术(IR,MS,1H-NMR,13C-NMR,HMQC和HMBC)和化学方法鉴定为26-O-β-D-葡萄吡喃糖基-(25R)-呋甾-5-烯-3β,17α-二羟基-3-O-[α-L-鼠李吡喃糖基(1-2)]-α-L-鼠李吡喃糖甙、木栓酮和豆甾醇。
Six compounds,friedelin,friedelan 3 β ol,methyl docosanoate,10 nonacosanol,stigamasterol and daphnetin 8 β D glucopyranoside were isolated from the plant of Aspidopterys obcordata Lemsl.
)中首次分离得到 5个化合物 ,通过波谱分析分别鉴定为木栓酮 (1)、无羁萜 - 3β-醇 (2 )、廿二烷酸甲酯 (3)、10 -廿九烷醇 (4 )、豆甾醇 (5 )和 daph-netin- 8- glucopyranoside(6
Crystal Ⅰ?Ⅱ?Ⅲ were determined as Friedelin,Epifriedelinol,Glochidone.
我们从永瓣藤乙醇提取物中分离到三种化合物 ,分别为木栓酮 (ｆｒｉｅｄｅｌｉｎ ,Ⅰ ) ,表木栓醇 (ｅｐｉｆｒｉｅｄｅｌｉｎｏｌ ,Ⅱ ) ,算盘子酮 (ｇｌｏｃｈｉｄｏｎｅ ,Ⅲ )。
Suberinite occurs commonly in Mesozoic coal measures and terrestrial organic matter source rocks in Northwest China, which is formed from suberized cell walls, particularly in plant periderm.
西北中生界煤系烃源岩中普遍含有木栓质体，它来源于植物周皮的木栓化细胞壁。
The composition of the pyrolysis products from Changguang suberinite is iden-tified by using the sequential flash pyrolysis gas chromatography and pyrolysis gas chro-matography-mass spectrometry.
用等温热解气相色谱（Ｐｙ－ＧＣ）法以及热解气相色谱质谱（Ｐｙ－ＧＣ－ＭＳ）联用技术，结合元素分析，探讨了我国浙江省长广煤木栓质体的热解特征。