HLA-DQB_1 genes involved in the genetic susceptibility of gastric ulcer in Guangdong Hans;
广东地区汉族人HLA-DQB_1基因对胃溃疡患者的遗传易感性研究
Relativity study of HLA class Ⅱ gene polymorphism and gestational diabetes mellitus;
山西地区HLA-Ⅱ类基因多态性与妊娠期糖尿病的相关性研究
Progress in study on correlation between HLA class Ⅱ gene and human pregnancy-induced disorders;
HLA-Ⅱ类基因与人类妊娠期特定疾病的相关性
HLA-DR genotypes were detected by SSP-PCR in 40 patients with acquired aplastic anemia and 107 normal controls, and the expressions of HLA-DR gene in AA patients and normal controls were compared.
本研究探讨再生障碍性贫血(AA)患儿HLA-DR基因表达情况及其与免疫抑制治疗疗效的关系,评价HLA-DRB1*15基因型检测的临床意义。
Objective:To evaluate relationship between HLA and IgA nephropathy,we study HLA-DR gene susceptibility to IgA nephropathy in Guangxi Zhuang population.
目的:探讨广西籍壮族IgA肾病(IgAN)与HLA-DR基因的相关性,并进行序列分析。
Objective: To evaluate relationship between HLA and IgA nephropathy and it’s clinical presentation，pathology, We study HLA-DR gene susceptibility to IgA nephropathy in Guangxi Zhuang and Han population.
目的：探讨广西地区汉族、壮族IgA肾病（IgAN）与人类白细胞抗原（HLA）-DR基因的相关性，以及其临床表现、病理改变与HLA-DR基因的相关性。
To investigate the correlation between the HLA genes and pathogenesis of aplastic anemia (AA), polymerase chain reaction with specific sequence primers (PCR-SSP) method was used to HLA typing in 82 patients with AA and 400 normal healthy individuals as control.
本研究探讨HLA基因与再生障碍性贫血(aplastic anemia,AA)发病之间的相关性。
The HLA gene types in 30 DMD patients were compared with those of 668 unrelated donors from Umbilical Cord Blood Center of Guangdong Province .
结果表明 :DMD疾病组的HLA基因呈正态遗传 ,DMD患者HLA基因表达与广东健康人群无统计学上显著差异 ;DMD患者中 1/ 4寻找到合适用于移植的干细胞 ,其中在广东脐血库寻找到≥ 5个HLA ABDR基因配合的几率为 5 0 % ,在中国造血干细胞库寻找到 6个HLA ABDR基因配合的几率为 2 6%。
Methods The vector containing HLA-DRα gene as standard template was constructed by T-A cloning technique.
目的建立实时荧光定量反转录聚合酶链反应(RT-PCR)法检测HLA-DRα基因mRNA表达。
Objective To set up the method for analyzing HLA-B gene polymorphism with PCR-RFLP, and to gain population data among northern Chinese Hans of HLA-B′s restricted fragments after NlaIII digestion, and to achieve application in forensic medicine practice.
目的建立以PCR-RFLP法分析HLA-B基因多态性的方法,并对105名北方汉族人群酶切片段类型、频率进行调查,为其法医学应用奠定基础。