Effect of 5-Aza-2'-deoxycytidine on biological behaviors of human breast cancer cell line MCF-7;
5-氮杂-2′-脱氧胞苷对MCF-7乳腺癌细胞生物学行为影响的研究
OBJECTIVE:To investigate the effects of 5-Az-a-2 -deoxycytidine(5-Aza-CdR) and trichostatin A(TSA) on the proliferation of MDA-MB-435S cells and the expression of tumor suppressor gene maspin.
目的:研究5-氮-2′-脱氧胞苷(5-A-za-CdR)和曲古菌素A(TSA)对乳腺癌MDA-MB-435S细胞增殖及抑癌基因maspin表达的影响。
1 μmol/L, 1 μmol/L, 5 μmol/L,10 μmol/L) of 5-aza-2′-deoxycytidine(5-aza-2dC) were added into culture medium of NPC cell lines for 72 hours′ de-methylation treatment, then methylation status of ANXA1 gene were detected by MSP and mRNA expression were evaluated by RT-PCR.
然后用不同浓度的5-杂氮-2′-脱氧胞苷(5-aza-2dC)对NPC细胞进行去甲基化处理,MSP和RT-PCR方法检测处理组和对照组细胞ANXA1基因甲基化状况和mRNA表达水平,并用Western-blotting方法检测ANXA1基因蛋白质表达水平。
deoxycytidine monophosphate
脱氧胞苷（一磷）酸
deoxycyti - dylate hydroxymethylase
脱氧胞苷酸羟甲基化酶
Effect of 5-Aza-dC on FHIT gene expression in non-small cell lung cancer cell line A549
5-氮杂脱氧胞苷对非小细胞肺癌细胞A549中抑癌基因FHIT表达的影响
Effect of 5-aza-2’-deoxycytidine on MEG3 gene expression and proliferation of human mammary cancer line MCF7
5-氮杂脱氧胞苷对MCF7细胞中MEG3基因表达及细胞增殖活性的影响
Effect of the Demethylating Agent 5-Aza-2 -deoxycytidine on SW48 Human Colonic Carcinoma Cell Lines;
5-氮杂-2’-脱氧胞苷对SW48结肠腺癌细胞生物学行为的影响
Effect of 5-Aza-2 -deoxycytidine on Biological Behaviors of Human Breast Cancer Cell Line MCF-7;
5-氮杂-2 -脱氧胞苷对乳腺癌细胞MCF-7生物学行为的影响
Reseach of Apoptosis in Cartilage Cells of Rabbit Induced by 5-aza-CdR;
5-氮杂脱氧胞苷诱导兔软骨细胞凋亡的实验性研究
5-Aza-2-deoxyctidine on Cell Cycle, Chromosome and Apoptosis of Fibroblast
5-氮-2-脱氧胞苷对牛成纤维细胞周期、染色体和凋亡的影响
Study of the Effect of 5-aza-2-deoxycytine and Trichostatin A on Growth Inhibition in Gastric Cancer Cells
5-氮-2-脱氧胞苷与曲古抑菌素A对胃癌细胞生长抑制作用的研究
Effect of 5-Aza-dC on FHIT gene expression in hepatocellular carcinoma cell line HepG2
5-氮杂脱氧胞苷对肝癌细胞HepG2中抑癌基因FHIT表达的影响
Effects of 5-Aza-2'-deoxycytidine on expression of RUNX3 and biological behaviors of T24 bladder cancer cell line
5-氮-2’-脱氧胞苷对膀胱癌T24细胞株RUNX3表达及生物学行为的影响
Reversion transcriptional expression of DAPK in bladder cancer T24 cells 5-aza-2'-deoxycytidine
5-杂氮脱氧胞苷逆转膀胱癌T24细胞死亡相关蛋白激酶的转录表达
The effect of combination of 5-Aza-2′-deoxycytidine with Paclitaxel on gastric cancer cells
5-氮杂-2′-脱氧胞苷联合紫杉醇对中分化胃腺癌细胞株SGC-7901的作用
Effect of 5-Aza-2’-deoxycytidine on growth inhibition of renal carcinoma cell line OS-RC-2 and reversion of γ-catenin gene hypermethylation
5-氮杂-2’-脱氧胞苷抑制肾癌细胞增殖及逆转γ-catenin基因甲基化作用
Effect of 5-Aza-2'-deoxycytidine on human renal cell carcinoma cell line OS-RC-2
5-氮杂-2′-脱氧胞苷对OS-RC-2肾癌细胞生物学行为的影响
5-aza-dC influences proliferation and apoptosis of human lung cancer cell line A549
5-氮-2′-脱氧胞苷对人肺癌A549细胞株增殖和凋亡的影响
Effect of the 5-Aza-dc on RUNX3 gene demethylation in T24 bladder cancer line at transcriptional level
5-氮-2′脱氧胞苷对T24膀胱癌细胞RUNX3基因去甲基化的转录调节作用
deoxyguanosine monophosphate
脱氧鸟苷（一磷）酸