The effect of mobile phase composition on enantioseparation of naproxen and its derivatives on a commercial high performance liquid chromatographic column packed with a chiral stationary phase(CSP) of(R,R)-Whelk-O 1 was investigated.
在正相色谱条件下,对萘普生及其衍生物系列在(R,R)-Whelk-O 1手性固定相(chiral stationary phase,CSP)上进行了对映体拆分研究。
Direct enantioseparations of seven N-fluorenylmethoxycarbonyl-amino acids (Fmoc-Val,Fmoc-Ser,Fmoc-Leu,Fmoc-Ile,Fmoc-Met,Fmoc-Ala,and Fmoc-Phe) were achieved by high performance liquid chromatography using a 250 mm×4.
比较了Fm o c-缬氨酸和相应的不带保护基的缬氨酸对映体在不同流动相体系中的色谱保留行为;考察了甲醇-醋酸-三乙胺流动相体系中醋酸和三乙胺的浓度以及它们二者的浓度之比对N-Fm o c氨基酸对映体拆分效果的影响。
Tartaric acid derivatives have been widely used in enantioseparation and asymmetric synthesis.
酒石酸衍生物在对映体拆分和不对称合成中得到广泛应用。
A high performance liquid chromatographic method has been developed for the enantiomeric separation of trimebutine maleate (TBM) and ondansetron (OND) on a Chiralpak AD-H Chiral column under normal phase mode .
使用Chiralpak AD-H手性色谱柱,采用正相洗脱方式,考察了流动相中有机改性剂的种类和浓度、酸碱比(冰乙酸-三乙胺)、柱温及流速等因素对对映体拆分的影响。
Study of the enantiomers resolution mechanism of chiral amide pharmaceuticals by capillary electrophoresis
毛细管电泳氨类手性药物对映体拆分机理研究
Resolution of sibutramine enantiomers with α_1-AGP chiral stationary phase
α_1酸性糖蛋白柱拆分西布曲明对映体
Study of Chiral Separation of Tryptophan Enantiomers and Process Simulation;
色氨酸对映体的手性拆分及过程模拟
Direct resolution of citalopram enantiomers by chiral stationary phase using CHIRAEL OJ-H column
OJ-H柱拆分西酞普兰对映异构体
Chiral Separations of Selected Pharmaceuticals on Brush-Type Chiral Stationary Phases;
刷型手性固定相对于药物对映体的拆分研究
Enantiomeric Separation of Dethmor by High Performance Capillary Electrophoresis
杀鼠灵对映体的高效毛细管电泳手性拆分
Application and Study of the Enantioselective Separation of Chiral Drugs by HPLC;
高效液相色谱法拆分药物对映体及其机理探讨
Separation and Quantitation of Theanine Enantiomer by High Performance Liquid Chromatography;
茶氨酸对映体的高效液相色谱拆分与定量
Study on the Separation and Toxicity of Enantiomers of Beta-Cypermethrin;
高效氯氰菊酯的手性拆分及其对映体毒性研究
Study on Chiral Resolution of Enantiomers of β-adrenergic Drugs;
β-肾上腺素类药物对映体的手性拆分研究
Enantionmeric Separation of Ketorolac Tromethamine by HPLC;
高效液相色谱法拆分酮咯酸氨丁三醇盐对映体
Direct chiral separation of naftopidil enantiomers by RP-HPLC using Chiralpak AD-RH
Chiralpak AD-RH手性柱直接拆分萘哌地尔对映体
Direct Chiral Separation of Propafenone Enantiomers by RP-HPLC Using Chiralpak AD-RH
CHIRALPAK AD-RH手性柱直接拆分普罗帕酮对映体
Direct chiral separation of indapamide enantiomers by RP-HPLC using CHIRALCEL OD-RH
CHIRALCEL OD-RH手性柱直接拆分吲达帕胺对映体
Chiral Separations of BCEC-Cl-Derivatized Amino Acids by Micellar Electrokinetic Capillary Chromatography
氨基酸对映体的胶束电动毛细管色谱拆分研究
Chiral Separation of Enantiomers of Quinolone Drugs by Capillary Electrophoresis
毛细管电泳手性拆分喹诺酮类药物对映体
Chiral Separation of Ofloxacin Enantiomers by High Performance Capillary Electrophoresis
氧氟沙星对映体的高效毛细管电泳法手性拆分
Chiral separation of cidofovir by reversed-phase high performance liquid chromatography
西多福韦对映体的拆分及异构体含量分析方法研究