Therapy with endogenous angiogenesis inhibitor is not clinically practical because of the high doses required and the difficulty in producing them in a fully functional state.
肿瘤抑素(Tumstatin)是继血管生成抑素(Angiostatin)和内皮抑素(Endostatin)之后,新发现的源于血管基膜Ⅳ型胶原α3链的内源性血管生成抑制因子,具有明显的抑制肿瘤血管生成和诱导其内皮细胞调亡的活性。
Based on its function of blocking the new blood vessel forming of tumor,and with its safety,the use foreground of angiogenesis inhibitors as an anti-tumor drug was broad.
血管生成抑制因子是近年来迅速发展的一类具抑制血管新生和抗癌作用的蛋白质,它在人体内能安全使用,并且不产生抗药性,有着广阔的应用前景。
Cloning of the gene coding for tumor angiogenesis inhibitor Arresten and its transference to Nicotiana tabacum;
肿瘤血管生成抑制因子Arresten基因克隆及其对烟草的转化
Molecular Cloning and Transgenic Research of the Genes Encoding Taxadiene Synthase and Tumor Angiogenesis Inhibitor;
紫杉二烯合成酶及肿瘤血管生成抑制因子基因克隆与转基因研究
Cloning, Expression, Purification of Endogenous Angiogenesis Inhibitor Arresten Gene and Its Biological Activity Detection;
内源性血管生成抑制因子Arresten基因的克隆、表达、纯化及活性的测定
The optimization of the recombinant Shark Cartilage Angiogenesis Inhibiting Factor's fermentation conditions
基因重组鲨鱼软骨血管生成抑制因子的发酵条件优化
Inhibition Function of Vascular Endothelial Growth Factor Antibody on the Growth and Angiogenesis of Human Osteosarcoma;
血管内皮生长因子抗体抑制骨肉瘤生长及血管生成的实验研究
Research progress in inhibition of corneal neovascularization by anti-VEGF therapy
抑制血管内皮生长因子活性治疗角膜新生血管形成
Effect of Angiogenesis Inhibitors, IFN-α and IFN-γ on Lymphangiogenesis;
血管内皮抑制因子IFN-α和IFN-γ对淋巴管内皮细胞生成的影响
Influence of Angiogenesis Inhibitors, Endostatin and PF-4, on the Lymphagiogenesis;
血管内皮抑制因子Endostatin和PF-4对淋巴管内皮细胞生成的影响
The Experimental Study of Pigment Epithelial-derived Factor Suppressing Retinal Neovascularization in Mice;
色素上皮衍生因子抑制小鼠视网膜新生血管形成的实验研究
The Study of Qilian Shupi Granule in Treating Precancerous Lesions of Chronic Atrophic Gastritis in Clinic and Inhibiting Factors;
芪莲舒痞颗粒对CAG癌前病变临床及抑制血管生成因子的研究
The Study of Kun Shen Granule Antiangiogenesis Factors of VEGF and in Treating Advanced Gastric Cancer in Clinic;
“昆参颗粒”抑制血管生成因子（VEGF）治疗进展期胃癌的研究
Cloning and Expression of Angiostatin;
肿瘤血管生长抑制因子Angiostatin基因的克隆及表达
The Molecular Mechanism Study of EGCG on the Inhibition of Nasopharyngeal Carcinoma Angiogenesis;
EGCG抑制鼻咽癌血管生成的分子机制研究
The Inhibition of Combined Transfection of p53 and AS Genes into K562;
共转染p53和血管生成抑素基因对人髓白血病K562细胞的抑制作用
The Separation and Purification of Recombinant Angiogenesis Inhibitor Kringle 5;
重组血管生长抑制因子Kringle 5的分离纯化
A Mechanism of UCN s Protective Role in Diabetic Nephropathy: Inhibiting Vascular Endothelial Growth Factor;
Urocortin抑制血管内皮生长因子改善糖尿病肾病
Targeted inhibition of vascular endothelial growth factor in glaucoma therapy
靶向性抑制血管内皮生长因子与青光眼治疗
Study on the Transfection of Mouse Interleukin-12 Gene Inhibiting the Angiogenesis of Hepatocarcinoma of Nude Mouse;
mIL-12基因转染抑制裸鼠肝癌血管生成的研究
Inhibitory Effect of siRNA Targeting Against EPAS1 on Angio-genesis in Pancreatic Carcinoma of Nude Mice
siRNA沉默EPAS1基因抑制裸鼠胰腺癌模型血管生成