DNA damage level, expression level of DNA damage repair enzymes such as cross-complementing rodent repair deficiency gene 1(ERCC1) ,uracil DNA glyco-sylase(UDG), O6-methylguanine-DNA methyltransferase(MGMT), DNA-dependent protein kinase catalytic subunit(DNA-PKcs) , hMSH2 were measured.
5种DNA损伤修复酶表达水平在1μmol/L、10μmol/L、50μmol/L剂量组依次降低,在100μmol/L、100μmol/L+VitC组依次增加,50μmol/L组各种DNA。
Objective To examine the effect of heat stress on the expression of HSP70 and XPA repair enzyme in A549 cell line.
目的研究热应激作用下A549细胞热休克蛋白70(HSP70)和XPA修复酶的表达规律及其可能的意义。
hMSH2 deficiency of DNA repair enzyme and cell genetic stability;
DNA修复酶hMSH2缺陷与细胞遗传不稳定性
Structures and functions of DNA repair enzymes;
DNA修复酶的结构和功能
The activity of DNA photolyase in vitro;
DNA光修复酶体外活性的研究