The results of the separation indicated 5′-deoxymononucleotides components could be full.
论述了用桔青霉PenicilliumcitrinumM71菌株 ,经液体培养制得的 5′ -磷酸二酯酶降解鲐鱼鱼精DNA成5′ -脱氧核苷酸的分离工艺。
Establishment,optimization and application of a screening method for immunoregulatory oligodeoxynucleotides;
免疫调节性寡聚脱氧核苷酸筛选方法的建立、优化和应用
Sequence designation and screening of novel immunoregulatory oligodeoxynucleotides;
新型免疫调节性寡聚脱氧核苷酸的序列设计和筛选分析
Evaluation of Immunostimulatory Activities of Human CpG-ODN Containing 5 -GTCGTT-3 Motif in Murine Model;
利用小鼠模型评价含有5 -GTCGTT-3 特征序列的人CpG寡脱氧核苷酸的免疫刺激活性
With more reports of the immune activities of nucleotide,CpG oligodeoxynucleotides(ODN) showed broad application in induction of innate immune activation,as a vaccine adjuvant,immunotherapy for allergy,anticancer applications and gene therapy.
随着对CpG特性研究的不断深入,CpG寡脱氧核苷酸在激活先天性免疫、作为疫苗佐剂、对变态反应进行免疫治疗、抗肿瘤应用及基因治疗等方面均显示出较广阔的应用前景。