Objective To prepare a bispecific antibody (BsAb) against CD3 and TNP and to test its cytotoxic effect against the gastric cancer cell line,MGC803.
:目的 以化学方法将抗CD3 及抗三硝基苯 (TNP)单克隆抗体交联为双功能抗体 ,研究此双功能抗体与任何TNP化的抗肿瘤单抗结合 ,介导对肿瘤细胞的杀伤作用。
Synthesis of 2,4,6-trinitrophenylhydrazine;
2,4,6-三硝基苯肼的合成
Polynitropolyphenylene( PNP ) ,as binder, has high heat-resistance , with three nitryl groups at 1-,3-,5-position in a.
聚三硝基苯作为粘结剂属于多硝基芳香族化合物,分子中三个硝基以对称性结构排布在苯环上,使聚三硝基苯具有优良的耐热安全性。