As an important side chain intermediate, 3-thiophenemalonic acid (3-TMA) can react with 6APA to produce Ticarcillin which can be prepared from Benzylpenicillin and penicillin analysis by degradation under alkaline conditions.
噻吩丙二酸(TMA)作为重要的侧链中间体与6-氨基青霉烷酸(6APA)反应,可以制备青霉素类β-内酰胺抗生素替卡西林(A),而6-氨基青霉烷酸(6APA)可利用苄青霉素为原料,在偏碱性的条件下,经青霉素酰化酶(Penicilln acylase)酶解生成,具体反应式如下:替卡西林(A)与克拉维酸钾以15:1组合形成的药物一泰门汀(Timentin)是一种强力抗生素。
3-thienylmalonic acid has pharmaceutical importance as the side-chain intermediate used in the production of the semisynthetic β-lactam antibiotic ticarcillin(A).
3-噻吩丙二酸是重要的青霉素类β-内酰胺抗生素替卡西林(A)的中间体。
ticarcillin-clavulnic acid
替卡西林-克拉维酸
Ticarcillin Sodium and
替卡西林钠克拉维酸钾
Subs: Jones, Queudrue, Ehiogu, Johnson, Viduka.
替补：琼斯，奎杜，埃西奥古，约翰森，维杜卡。
74 Chelsea substitutions J Cole for Mikel, Wright-Phillips for Kalou.
74分?切尔西换人：乔．科尔入替米克尔，赖特．菲利普斯入替卡劳。
45 Chelsea substitution Half-time change as Pizarro replaces Kalou up front.
第45分钟，切尔西换人：皮萨罗替换卡劳上场。
This is Vera Carlinho from the Brazil office.
我是巴西办事处的维拉·卡林霍。
Discovery Coast Atlantic Forest Reserves
迪斯卡弗里海岸的大西洋森林保护区
Fluoxetine combined with maprotiline in treating depressive disorder associated with anxiety
氟西汀联用马普替林治疗抑郁伴发焦虑障碍
Comparative Study of Duloxetine and Amitriptyline in Treating Patients with Depression
度洛西汀与阿米替林治疗抑郁症的对照研究
Comparison on the efficacy of paroxetine and amitriptyline in acute burnt patients with psychological disorders
帕罗西汀与阿米替林对烧伤后情绪的疗效比较
Giuseppe Rossi made his debut for Newcastle as a second half substitute.
罗西在下半场替补出场，完成了在纽卡斯尔的处子秀。
Research on Origin between High-Arsenic Coal and Carlin-type Gold Deposit in Southwestern of Guizhou Province;
黔西南高砷煤与卡林型金矿成因关系研究
A Mineralization Mechanism as Well as Minerogenetic Prospect of Carlin-type Gold Deposit in Southwestern of Guizhou;
黔西南卡林型金矿的成矿机制及成矿预测
Mineralization Characteristics and Prospecting Indicator of Carlin-type Gold Deposits in Western Jiangxi
赣西卡林型金矿的成矿特征及找矿标志
Comparison of Soil Properties under Different Successional Series of Subalpine Coniferous Forests in Western Sichuan;
川西亚高山针叶林不同演替阶段土壤特性比较研究
Teicoplanin Used for Severe Infected Patients with MRSA in Intensive Care Unit
替考拉宁治疗ICU耐甲氧西林金黄色葡萄球菌感染的疗效观察
A comparative study of citalopram and maprotiline in the treatment of elderly depressive
西酞普兰与马普替林治疗老年抑郁症的对照研究
A META-ANALYSIS ON RANDOMIZED CONTROLLED TRIALS OF CITALOPRAM VERSUS AMITRIPTYLINE IN ELDERLY DEPRESSED PATIENTS
西酞普兰与阿米替林治疗老年抑郁症随机对照试验的Meta分析