Preparation of Clarithromycin Floating Beads and Research on its Release Behavior in Vitro;
克拉霉素胃漂浮小丸的制备及其体外释药研究
Objective of the research is to prepare a Cla floating beads,in which all Cla can be released within 5 hours at zero rate in stomach.
本研究的目的是将Cla制成胃漂浮小丸,使其在胃局部大约5小时左右零级释放全部药物。
Guar gum/ethylcellulose coated pellets for colon-specific drug delivery;
结肠定位释药瓜尔胶/乙基纤维素包衣小丸(英文)
Methods Nifedipine solid dispersion drug pellets were prepared by fluid bed with polyvinylpyrrolidone(PVP).
方法采用流化床包衣法,将硝苯地平与聚乙烯吡咯烷酮溶于90%乙醇喷于空白丸芯制成固体分散体含药小丸,以含有致孔剂的乙基纤维素水分散体(SureleaseR)作为包衣材料进行包衣,得小丸装胶囊。
Objective: The gelatinization characteristics of carboxymethyl konjac glucomannan(CMKGM) with metal ion or chitosan were studied to elevate the feasibility of CMKGM used as a new carrier material to prepare multiple-unit dosage form-pellets.
目的:考察羧甲基魔芋胶与金属离子和壳聚糖的凝胶化性能,评价其作为多剂量分散型制剂-小丸剂的载体材料的可行性。