Purpose To invesigate the effect of glucocortioid on the nuclear protein level of glucocorticoid receptor(GR),activator protein-1(AP?1) and nuclear factor-kappa B(NF?κB),and the relationship between this effect and the glucocorticoid sensitivity in idiopathic nephrotic syndrome(INS).
目的 探讨特发性肾病综合征 (INS)患者糖皮质激素受体 (GR)、核因子κB(NF κB)和活化蛋白 1(AP 1)的核内蛋白水平受糖皮质激素治疗的影响 ,以及这种变化与激素敏感性的关系。