Deferoxamine protects against amikacin ototoxicity and ist mechanism;
甲磺酸去铁胺抗丁胺卡那霉素耳毒性作用及机理研究
Objective To observe the change of mitochondrion membrane potential(ΔΨm) in apoptosis induced by an iron chelator(deferoxamine,DFO),and to explore the mechanism of this apoptosis in human leukemia-60(HL-60) cells.
方法HL-60细胞分别与10、50、100μmol/L去铁胺(DFO)和10、100μmol/L三氯化铁(FeCl3)共培养,分别造成细胞内铁剥夺和富铁状态,噻唑蓝(MTT)法检测不同铁状态下细胞活力变化;相差显微镜观察凋亡细胞的形态学改变,流式细胞仪(FCM)检测细胞凋亡率及ΔΨm变化;原位杂交法检测凋亡基因Bax转录水平。
This study was purposed to observe the changes of caspase-3 activity during apoptosis of HL-60 cells induced by an iron chelator, DFO (deferoxamine), and to explore the mechanism underlying apoptosis in HL-60 cells.
为了研究铁螯合剂—去铁胺(deferoxamine,DFO)诱导人白血病细胞株HL-60凋亡时半胱天冬酶-3(caspase-3)活性的变化并探讨DFO诱导凋亡的可能机制。
The Antiproliferative Effect of Desferrioxamine on K562 Cell and Its Influence on Cell Cycle;
去铁胺抗K562细胞的增殖作用及对细胞周期的影响
Mechanism of desferrioxamine activity in EMMPRIN expression in macrophages and foam cells
铁离子螯合剂去铁胺上调巨噬细胞、泡沫细胞细胞外基质金属蛋白酶诱导因子表达的机制探讨
Iron chelator desferrioxamine enhances EMMPRIN expression in THP-1-derived macrophages and foam cells
铁离子螯合剂去铁胺对巨噬细胞、泡沫细胞细胞外基质金属蛋白酶诱导因子表达的影响
Methods HL-60 cells were cultured in RPMI-1640 medium supplemented with 10% heat-inactivated fetal bovine serum which was treated with ferric chloride(FeCl3) or deferoxamine(DFO).
方法将FeCl3或去铁胺(Desferrioxamine,DFO)加入含有体积分数10%胎牛血清的RPMI-1640培养液中,使HL-60细胞处于缺铁或富铁的不同状态下培养。
To observe the effect of DFO on iron metabolism in primary cultured rats cardiac myocytes.
观察去铁胺(DFO)对原代培养的心肌细胞铁代谢的影响,探讨DFO对心肌细胞铁代谢的影响机制。
This is further supported by experiments with the iron chelator desferrioxamine.
对铁螯合剂去铁胺的研究也证实了这一观点。
Beneficial Effect of Deferoxamine in the Treatment of Ischemic Acute Renal Failure Rats;
去铁胺对缺血性急性肾衰竭大鼠的保护作用
A Exploratory-study of the cytoprotection of deferoxamine on endothelium under hypoxia
去铁胺对低氧内皮细胞保护作用机制的探讨
Meta-Analysis of the Efficacy and Safety of Combined Chelation Therapy in Patients with Thalassemia Major
去铁酮联合去铁胺治疗重型地中海贫血铁超负荷临床疗效及安全性的Meta分析
Neuroprotective Effects of Iron Chelator Desferal on Dopaminergic Neurons in the Substantia Nigra of Rats;
铁离子螯合剂去铁胺对大鼠黑质多巴胺能神经元保护作用机制的研究
Meta-analysis of the efficacy and safety of combined therapy with deferiprone and deferoxamine in thalassemia major patients
去铁酮和去铁胺治疗珠蛋白生成障碍性贫血临床疗效及安全性的Meta分析
Effect of Hypoxic Preconditioning or Desferrioxamine Preconditioning on High Altitude Pulmonary Edema and on HIF-1 Expression in Rats;
低氧和去铁胺习服对高原肺水肿大鼠的影响及HIF-1表达的研究
Iron chelator desferrioxamine enhances EMMPRIN expression in THP-1-derived macrophages and foam cells
铁离子螯合剂去铁胺对巨噬细胞、泡沫细胞细胞外基质金属蛋白酶诱导因子表达的影响
Study on Removal of Aniline by Enhanced Coagulation with Ferrate Pre-oxidation
高铁酸盐预氧化强化混凝法去除苯胺的研究
Iron filaments are drawn to a magnet
铁丝被磁铁吸了过去。
Synthetic Methods Studies on Ferrocenylketimines and Synthesis of Tertiary Ferrocenylamines;
乙酰基二茂铁亚胺合成方法学及苯甲酰二茂铁苄基叔胺的合成
ADSORPTION BEHAVIOR OF ALIPHATIC AMINES ON IRON SURFACE IN HCI SOLUTION
盐酸中伯胺在铁电极表面的吸附行为
Synthesis and Characterization of 1, 1 -Disubstituted Tertiary Ferrocenylamines;
1，1 -双取代二茂铁叔胺的合成及表征
Application Studty of Cyclometallated Ferrocenylimines;
二茂铁亚胺环金属化合物的应用研究
Polymerization of Ethylene Catalyzed by Novel 2,6-Bis(Imino) Pyridine Iron(Ⅱ) Complex
新型吡啶双亚胺铁催化乙烯聚合反应
Corrosion Inhibition Performance of Ethanolamine and KI for Iron with Low Content of Silicon and High Content of Sulfur
乙醇胺和KI对低硅高硫铁的缓蚀作用
Synthesis and characterization of diferrocenyl acidamide
双二茂铁基酰胺化合物的合成与表征
Preparation and Electromagnetic Properties of Poly(O/M-Toluidine-Aniline)-Ba Ferrite Composites
聚邻/间甲苯胺—苯胺—钡铁氧体复合物的制备及电磁性能研究