Mechanism of Tetrandrine in Combination with Droloxifen to Reverse Multidrug Resistance in Leukemia;
汉防己甲素联合屈洛昔芬逆转白血病细胞多药耐药机理研究
The aim of this study was to investigate the mechanism to reverse the drug resistance of leukemia cells in tetrandrine (Tet) alone or in combination with droloxifen (Drol) by using protein chips and to lay the theoretical basis for the clinical applications.
本研究的目的是应用蛋白质芯片检测汉防己甲素(Tet)单独及与屈洛昔芬(Drol)伍用对作用的白血病细胞表面的耐药蛋白,包括P糖蛋白(Pgp)、多药耐药相关蛋白(MRP1)、乳腺癌耐药蛋白(BCRP)表达的作用,为逆转剂的临床应用提供理论依据。
Objective: To evaluate protein array in detection of mutidrug-resistance proteins and investigate the reversal mechanism of the Tetrandrine(Tet) and Droloxifen(Drol) .
目的:对玻片表面化学修饰进行研究,探讨蛋白质芯片在检测白血病细胞MDR蛋白表达中的价值,以及进一步研究汉防己甲素和屈洛昔芬的逆转耐药机理,为两药的临床应用提供理论依据。
Effects of growth inhibition and apoptosis induction of droloxifene on mice brain microvascular endothelial cells bEnd.3;
屈洛昔芬抑制小鼠脑微血管内皮细胞bEnd.3增殖和诱导凋亡的作用
Reversal effect of tetrandrine in combination with droloxifene on cell line K562/A02 and the correlation with apoptosis induction;
汉防己甲素联合屈洛昔芬逆转K562/A02细胞耐药的研究
Reversal effects of droloxifene on multidrug resistance in adriamycin-resistant K562 cell line;
屈洛昔芬对K562耐阿霉素细胞株耐药性的逆转作用(英文)
Mechanism of Tetrandrine in Combination with Droloxifen to Reverse Multidrug Resistance in Leukemia;
汉防己甲素联合屈洛昔芬逆转白血病细胞多药耐药机理研究
Fading Spectrophotometric Method for the Determination of Raloxifene with Evans Blue
依文思蓝褪色分光光度法测定雷洛昔芬
Objective To synthesize raloxifene hydrochloride, which is a selective estrogen receptor modulator.
目的合成选择性雌激素受体调节剂盐酸雷洛昔芬。
Experimental Study of the Effects of Raloxifene on Cardiovascular System and the Molecular Mechanisms Involved;
雷洛昔芬的心血管作用及相关分子生物学机制研究
Modulation of Cardiac Ion Channels by Protein Tyrosine Kinases and Raloxifene;
蛋白酪氨酸激酶及雷洛昔芬对心肌离子通道调控作用的研究
Effects of Raloxifene on the Expression of Transforming Growth Factor-beta1 Gene in Ovariectomized Rats Bone;
雷洛昔芬对去卵巢大鼠骨组织TGF-β_1基因表达的影响
Effects of Raloxifene on the Prevention and Treatment of Osteoporosis in OVX Rats;
雷洛昔芬对卵巢切除大鼠骨质疏松症的防治作用
Effects of Raloxifene on Estrogen Receptor α and β、PPARγ mRNA of Bone and Uterus of Ovariectomized Female Rats;
雷洛昔芬对去势雌性大鼠骨、子宫内膜组织的ERs、PPARγ mRNA表达的影响
Comparison of the Effect of Flurbiprofen Axetil and Celecoxib on Adjuvant Arthritis in Rats
氟比洛芬酯与塞来昔布治疗大鼠佐剂性关节炎效果的比较
Intestinal Absorption Barricade Network and the Effect of Apigenin Influencing Bioavailability of Raloxifene;
黄酮类成分Apigenin影响肠吸收屏障网络及其提高雷洛昔芬生物利用度的研究
Combined Effects of Raloxifene and Estrogen on Bone and Other Target Organs in Ovariectomized Rats;
联合应用雷洛昔芬和雌激素对去势大鼠骨组织和其他靶器官的效应
The Role of Podocytes in Pathogenesis of Adriamycin-induced Nephropathy and Effects of Rapamycin and Raloxifene on Them in Rats
足细胞在多柔比星肾病大鼠病变过程中作用及雷帕霉素、雷洛昔芬对其影响
Effect of Tetredrine(TTD),Raloxifene and Their Combination on Reversion of Multidrug Resistance of Human Hepatocellular Carcinoma (HCC) Multidrug Resistant Cell Line (Hep-3B/ADM)
汉防己甲素、雷洛昔芬及其联合应用逆转人肝癌耐药细胞株多药耐药性的研究
Simultaneous and Rapid Determination of Aciclovir, Ganciclovir and Penciclovir in Plasma Using Solid-phase Extraction and High-performance Liquid Chromatography;
SPE-HPLC法同时快速测定血浆中更昔洛韦、阿昔洛韦和喷昔洛韦的浓度
Comparison of Effects of Ganciclovir and Acyclovir on Adult Varicella
更昔洛韦和阿昔洛韦治疗成人水痘的疗效比较
Method for determining ganciclovir quantity contained in ganciclovir cream
更昔洛韦乳膏中更昔洛韦含量测定方法的研究
Therapeutic effects of ganciclovir and aciclovir on varicella
更昔洛韦与阿昔洛韦治疗水痘临床疗效分析
THE EFFECTS OF TAMOXIFEN ON LYMPHOCYTE FUNCTION OF MICE
他莫昔芬对小鼠淋巴细胞功能的影响