Ubiquitin - proteasome pathway is a highly effective protein - degradation pathway in the eukaryotic cells.
泛素 - 蛋白酶体途径是真核细胞内一种高效蛋白降解途径.
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Skp 2 is an Fbp, which targets many ubiquitin - mediated degradation of G 1 - and S - phase regulators.
研究表明许多恶性肿瘤中存在着Skp2相关机制的异常, Skp2现已被认为是一种重要的癌基因.
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So abnormality of the ubiquitin - proteasome proteolytic pathway is closely related to many diseases, especially cancer.
泛素介导的蛋白质降解途径的异常与许多疾病特别是肿瘤的发生密切相关.
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Conclusion: GFPu - 1 clonal cells may be a sensitive indicator for the function of the ubiquitin - proteasome system.
结论: GFPu -1 克隆细胞是一种反映UPS功能的敏感指标.
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The mRNA expression of ubiquitin in rat EDL muscle was determined by northern blot analysis.
应用northernblot方法测定伸指长肌组织泛素mRNA的 表达变化,分析骨骼肌蛋白降解与泛素mRNA表达的关系.
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