The Study of Molecular Mechanism Underlying the Neurodegeneration of PS cDKO Mice and the Rescue Effects by Environmental Enrichment;
早老素双敲除小鼠神经退行性病变及复杂环境对其逆转作用的分子机理研究
Alzheimer\'s disease(AD) is the most common neurodegeneration disease in central nervous system,as characterized by the senile plaques(SP) and neurofibrillary tangles (NFT) presented in cortex.
为测试这种药物对于dKO小鼠的作用,本实验分别对2月龄和6月龄的dKO小鼠喂食5个月EUK4010后,通过组织学及行为学实验等方法检测其对dKO小鼠神经退行性症状的的影响。
Understanding the alteration in biological characteristics of aged T1A would be helpful for the research of neurodegenerative disease, in which astrocytes may play a critical role,and these findings Will lead to a new avenue to the clinical treatment of neurodegenerative disorders.
因此,探讨T1A生物学特性的改变情况有助于阐明其在神经退行性病变过程中的作用机制,为神经退行性病变的治疗提供新的思路。
Applications of RNAi in study of the mechanism and therapy of neurodegenerative diseases;
RNAi在神经退行性疾病发病机制及防治研究中的应用
Cochaperone CHIP and neurodegenerative diseases;
副监护子CHIP与神经退行性疾病
Bone marrow stromal cells and neural injury and neurodegenerative disease;
骨髓基质细胞与神经损伤和神经退行性疾病
Metal-Based Therapeutic Strategies of Neurodegenerative Diseases
基于金属的神经退行性疾病治疗策略
Relationship between NMDA receptors and neuro degenerative diseases
NMDA受体与神经退行性疾病的关系
Distribution of Neural Progenitor Cells and Neuroregeneration in Mouse Models of Neurodegenerative Diseases;
神经退行性疾病小鼠模型中神经祖细胞分布及神经元再生的研究
MDA can be a Marker to Follow Neurodegenerative Disease Progression;
丙二醛可用作神经退行性疾病进程的衡量指标
The Relationship of Cytoplasmic Dynein and Neurodegenerative Diseases
细胞质动力蛋白与神经退行性疾病的关系
Dynamic interplay between phosphorylation and O-glycosylation of neurofilaments in neurodegenerative diseases
神经丝蛋白质糖基化与磷酸化的相互调节和神经退行性疾病
The Role of Apoptosis in 2,5-Hexanedione Induced Neurodegeneration;
细胞凋亡在2.5-已二酮诱导的神经退行性变性中的作用
Experimental Study of the Role of Interleukin-18 in KA-induced Neurodegeneration in Hippocampus of Mouse;
海人藻酸所致的小鼠海马神经退行性改变中IL-18作用的实验研究
Microglia in Neurodegenerative Disease: Mechanism and Relevant Therapeutics;
小胶质细胞与神经退行性疾病——机制与相应治疗药物探讨
An in Vitro Study on the Immunoregulation of IFN-inducible T Cell Alpha Chemoattractant in Neurodegeneration;
I-TAC在神经退行性病变中免疫调节作用的体外研究
Endoplasmic Reticulum Associated Degradation (ERAD) of Neurodegenerative Disease Proteins
内质网关联降解通路对神经退行性疾病致病蛋白的降解调控
Research progress of phenylpropanoid glycosides on prevention and control of neurodegenerative diseases
苯丙素苷类化合物防治神经退行性疾病的研究进展
Application of PET/CT on the Research of Neurodegenerative Disease Animal Models
PET/CT影像技术在神经退行性疾病动物模型研究中的应用
Progression of RNA interference on pathogenesis and treatment of neurodegenerative diseases
RNA干扰在神经退行性疾病发病机制研究和治疗方面的进展
The Effects of Calorie Restriction on Neurodegenerative Phenotype in Forebrain-specific Presenilin-1 and Presenilin-2 Double Knockout Mice.;
限制热量摄入对前脑特异性早老素双敲除小鼠神经退行性病变的影响
These results suggest that the immortalized glial cell line could serve as an ideal vehicle for therapeutic gene delivery system to achieve a long-term gene therapy of neurodegenerative diseases.
这些结果表明永生化胶质细胞可以安全有效地用于神经退行性疾病的长效基因治疗。
Early onset Huntington disease: A neuronal degeneration syndrome
早期发病的亨廷顿舞蹈病:一种神经元退行性改变综合征
Study on the Relationship between Cu-Zn SOD Expression and the Neurodegeneration Caused by Chronic Aluminum Overload in Mice;
Cu-Zn SOD表达与铝过负荷致小鼠神经元退行性变的关系研究